王珊珊;韩永和;林志蓉;李敏;

• 1:福建师范大学生命科学学院
• 2:福建中医药大学中西医结合学院
• 3:福建师范大学环境科学与工程学院
• 4:福建省污染控制与资源循环利用重点实验室

摘要(Abstract)：

细菌纤维素是一种以革兰氏阴性细菌为主的多个菌属合成的天然有机高分子材料,与植物纤维素化学结构相同.微生物以葡萄糖为底物分子,通过多酶系系统合成的细菌纤维素纯度高、结晶度高、吸水能力强、稳定性好、生物安全性突出,目前已被广泛应用于食品、医药、电化学、环境修复等多个领域.综述了细菌纤维素的合成过程、理化性质及应用研究进展,并展望了未来研究的主要方向.

关键词(KeyWords)： 细菌纤维素;葡萄糖;生物合成;高分子材料;膳食纤维

Abstract:

Keywords:

基金项目(Foundation): 国家自然科学基金资助项目(41807110);; 近海流域环境测控治理福建省高校重点实验室开放基金资助项目(S1-KF1802);; 福建师范大学泉港石化研究院专项基金资助项目(2017YJY13);福建师范大学优秀研究生学位论文培育计划资助项目(LWPYB007)

作者(Author): 王珊珊;韩永和;林志蓉;李敏;

Email:

DOI:

参考文献(References)：

• [1]LING S,CHEN W,FAN Y,et al.Biopolymer nanofibrils:Structure,modeling,preparation,andapplications[J].Prog Polym Sci,2018,85:1-56.
• [2]MOLINA-RAMíREZ C,CASTRO M,OSORIO M,et al.Effect of different carbon sources on bacterial nanocellulose production and structure using the low pH resistant strain Komagataeibacter medellinensis[J].Materials,2017,10(6):639.
• [3]SHI Z,ZHANG Y,PHILLIPS G O,et al.Utilization of bacterial cellulose in food[J].Food Hydrocolloid,2014,35(2):539-545.
• [4]SHODA M,SUGANO Y.Recent advances in bacterial cellulose production[J].Biotechnol Bioproc E,2005,10(1):1-8.
• [5]AUGIMERI R V,VARLEY A J,STRAP J L.Establishing a role for bacterial cellulose in environmental interactions:Lessons learned from diverse biofilm-producing Proteobacteria[J].Front Microbiol,2015,6:1282.
• [6]KOIZUMI S,YUE Z,TOMITA Y,et al.Bacterium organizes hierarchical amorphous structure in microbial cellulose[J].Eur Phys J E,2008,26(1/2):137-142.
• [7]GAMA M,GATENHOLM P,KLEMM D.Bacterial nanocellulose-A sophisticated multifunctional material[M].Florida:CRC Press,2013:20-42.
• [8]HESTRIN S,ASCHNER M,MAGER J.Synthesis of cellulose by resting cells of Acetobacter xylinum[J].Nature,1947,159(4028):64-65.
• [9]CASTRO C,ZULUAGA R,PUTAUX J L,et al.Structural characterization of bacterial cellulose produced by Gluconacetobacter swingsii sp.from Colombian agroindustrial wastes[J].Carbohyd Polym,2011,84(1):96-102.
• [10]KLEMM D,SCHUMANN D,UDHARDT U,et al.Bacterial synthesized cellulose:artificial blood vessels for microsurgery[J].Prog Polym Sci,2001,26(9):1561-1603.
• [11]IGUCHI M,YAMANAKA S,BUDHIONO A.Bacterial cellulose:a masterpiece of nature's arts[J].J Mater Sci,2000,35(2):261-270.
• [12]CASTRO C,VESTERINEN A,ZULUAGA R,et al.In situ production of nanocomposites of poly(vinyl alcohol) and cellulose nanofibrils from Gluconacetobacter bacteria:Effect of chemical crosslinking[J].Cellulose,2014,21(3):1745-1756.
• [13]REINIATI I,HRYMAK A N,MARGARITIS A.Recent developments in the production and applications of bacterial cellulose fibers and nanocrystals[J].Cri Rev Biotechnol,2017,37(4):510-524.
• [14]AMANO Y,ITO F,KANDA T.Novel cellulose producing system by microorganisms such as Acetobacter sp.[J].J Biol Macromol,2005,5(1):3-10.
• [15]IYER P R,CATCHMARK J,BROWN N R,et al.Biochemical localization of a protein involved in synthesis of Gluconacetobacter hansenii cellulose[J].Cellulose,2011,18(3):739-747.
• [16]NAKAI T,SUGANO Y,SHODA M,et al.Formation of highly twisted ribbons in a carboxymethylcellulase gene-disrupted strain of a cellulose-producing bacterium[J].J Bacteriol,2013,195(5):958-964.
• [17]SUNAGAWA N,FUJIWARA T,YODA T,et al.Cellulose complementing factor (Ccp) is a new member of the cellulose synthase complex (terminal complex) in Acetobacter xylinum[J].J Biosci Bioeng,2013,115(6):607-612.
• [18]KAWANO S,TAJIMA K,UEMORI Y,et al.Cloning of cellulose synthesis related genes from Acetobacter xylinum ATCC23769 and ATCC53582:Comparison of cellulose synthetic ability between strains[J].DNA Res,2002,9(5):149-156.
• [19]ZHANG H,XU X,CHEN X,et al.Complete genome sequence of the cellulose-producing strain Komagataeibacter nataicola RZS01[J].Sci Rep,2017,7(1):4431.
• [20]MORGAN J L W,MCNAMARA J T,FISCHER M,et al.Observing cellulose biosynthesis and membrane translocation in crystallo[J].Nature,2016,531(7594):329-334.
• [21]BROWN JR R M.The biosynthesis of cellulose[J].Food Hydrocolloid,1987,1(5/6):345-351.
• [22]IANNINO N I D,COUSO R O,DANKERT M A.Lipid-linked intermediates and the synthesis of acetan in Acetobacter xylinum[J].J Gen Microbiol,1988,134(6):1731-1736.
• [23]COUSINS S K,BROWN JR R M.Photoisomerization of a dye-altered β-1,4 glucan sheet induces the crystallization of a cellulose-composite[J].Polymer,1997,38(4):903-912.
• [24]COUSINS S K,BROWN JR R M.Cellulose I microfibril assembly:Computational molecular mechanics energy analysis favours bonding by van der Waals forces as the initial step in crystallization[J].Polymer,1995,36(20):3885-3888.
• [25]YAMANAKA S,WATANABE K,KITAMURA N,et al.The structure and mechanical properties of sheets prepared from bacterial cellulose[J].J Mater Sci,1989,24(9):3141-3145.
• [26]MEZA-CONTRERAS J C,MANRIQUEZ-GONZALEZ R,GUTIéRREZ-ORTEGA J A,et al.XRD and solid state 13C-NMR evaluation of the crystallinity enhancement of 13C-labeled bacterial cellulose biosynthesized by Komagataeibacter xylinus under different stimuli:A comparative strategy of analyses[J].Carbohyd Res,2018,461(4):51-59.
• [27]CHAWLA P R,BAJAJ I B,SURVASE S A,et al.Microbial cellulose:Fermentative production and applications[J].Food Technol Biotechnol,2009,47(2):107-124.
• [28]YOSHINAGA F,TONOUCHI N,WATANABE K.Research progress in production of bacterial cellulose by aeration and agitation culture and its application as a new industrial material[J].Biosci Biotech Bioch,1997,61(2):219-224.
• [29]MOREIRA S,SILVA N B,ALMEIDA-LIMA J,et al.BC nanofibres:In vitro study of genotoxicity and cell proliferation[J].Toxicol Lett,2009,189(3):235-241.
• [30]PéRTILE R A N,MOREIRA S,DA COSTA R M G,et al.Bacterial cellulose:Long-term biocompatibility studies[J].J Biomat Sci-Polym E,2012,23(10):1339-1354.
• [31]HUANG Y,ZHU C,YANG J,et al.Recent advances in bacterial cellulose[J].Cellulose,2014,21(1):1-30.
• [32]GULLO M,CHINA S L,FALCONE P M,et al.Biotechnological production of cellulose by acetic acid bacteria:Current state and perspectives[J].Appl Microbiol Biot,2018,102(16):6885-6898.
• [33]GAMA M,GATENHOLM P,KLEMM D.Bacterial nanocellulose-A sophisticated multifunctional material[M].Florida:CRC Press,2013:143-156.
• [34]GRUMEZESCU A M,HOLBAN A M.Food biosynthesis[M].Utah:Academic Press,2017:213-249.
• [35]OKIYAMA A,MOTOKI M,YAMANAKA S.Bacterial cellulose Ⅱ.Processing of the gelatinous cellulose for food materials[J].Food Hydrocolloid,1992,6(5):479-487.
• [36]NG C C,SHYU Y T.Development and production of cholesterol-lowering Monascus-nata complex[J].World J Microb Biot,2004,20(9):875-879.
• [37]王玮瑜.果汁细菌纤维素生产及功能性研究[D].西安：西北农林科技大学，2013.
• [38]CHAU C F,YANG P,YU C M,et al.Investigation on the lipid- and cholesterol-lowering abilities of biocellulose[J].J Agr Food Chem,2008,56(6):2291-2295.
• [39]NGUYEN V T,GIDLEY M J,DYKES G A.Potential of a nisin-containing bacterial cellulose film to inhibit Listeria monocytogenes on processed meats[J].Food Microbiol,2008,25(3):471-478.
• [40]XIAO L,MAI Y,HE F,et al.Bio-based green composites with high performance from poly (lactic acid) and surface-modified microcrystalline cellulose[J].J Mater Chem,2012,22:15732-15739.
• [41]JONAS R,FARAH L F.Production and application of microbial cellulose[J].Polym Degrad Stabil,1998,59(1/3):101-106.
• [42]CZAJA W K,YOUNG D J,KAWECKI M,et al.The future prospects of microbial cellulose in biomedical applications[J].Biomacromolecules,2007,8(1):1-12.
• [43]BUTCHOSA N,BROWN C,LARSSON P T,et al.Nanocomposites of bacterial cellulose nanofibers and chitin nanocrystals:Fabrication,characterization and bactericidal activity[J].Green Chem,2013,15(12):3404-3413.
• [44]TAMAYO L,AZóCAR M,KOGAN M,et al.Copper-polymer nanocomposites:An excellent and cost-effective biocide for use on antibacterial surfaces[J].Mat Sci Eng C-Mater,2016,69:1391-1409.
• [45]MEFTAHI A,KHAJAVI R,RASHIDI A,et al.The effects of cotton gauze coating with microbial cellulose[J].Cellulose,2010,17(1):199-204.
• [46]HAN Y H,MAO H L,WANG S S,et al.Ecofriendly green biosynthesis of bacterial cellulose by Komagataeibacter xylinus B2-1 using the shell extract of Sapindus mukorossi Gaertn.as culture medium[J].Cellulose,2020,27(3):1255-1272.
• [47]SILVA N H C S,RODRIGUES A F,ALMEIDA I F,et al.Bacterial cellulose membranes as transdermal delivery systems for diclofenac:In vitro dissolution and permeation studies[J].Carbohyd Polym,2014,106:264-269.
• [48]HUANG L,CHEN X,NGUYEN T X,et al.Nano-cellulose 3D-networks as controlled-release drug carriers[J].J Mater Chem B,2013,1(23):2976-2984.
• [49]NARH C,CHARLES F,MENSAH A,et al.Synthesis of highly stable bacterial cellulosic pocket for drug storage[J].Carbohyd Polym,2019,206(49):625-632.
• [50]MüLLER A,ZINK M,HESSLER N,et al.Bacterial nanocellulose with a shape-memory effect as potential drug delivery system[J].RSC Adv,2014,4(100):57173-57184.
• [51]SHI X,ZHENG Y,WANG G,et al.pH- and electro-response characteristics of bacterial cellulose nanofiber/sodium alginate hybrid hydrogels for dual controlled drug delivery[J].RSC Adv,2014,4(87):47056-47065.
• [52]SHAH J,BROWN JR R M.Towards electronic paper displays made from microbial cellulose[J].Appl Microbiol Biot,2005,66(4):352-355.
• [53]WU Z Y,LIANG H W,CHEN L F,et al.Bacterial cellulose:A robust platform for design of three dimensional carbon-based functional nanomaterials[J].Accounts Chem Res,2016,49(1):96-105.
• [54]GUAN F,CHEN S,SHENG N,et al.Mechanically robust reduced graphene oxide/bacterial cellulose film obtained via biosynthesis for flexible supercapacitor[J].Chem Eng J,2019,36:829-837.
• [55]郭必泛，洪秋林，陈乐瑞，等.石墨烯/细菌纤维素复合材料的原位生物合成[J].杭州师范大学学报(自然科学版),2020,19(2):127-131,158.
• [56]CHEN L F,HUANG Z H,LIANG H W,et al.Flexible all-solid-state high-power supercapacitor fabricated with nitrogen-doped carbon nanofiber electrode material derived from bacterial cellulose[J].Energ Environ Sci,2013,6:3331-3338.
• [57]CHEN L F,HUANG Z H,LIANG H W,et al.Bacterial-cellulose-derived carbon nanofiber@MnO2 and nitrogen-doped carbon nanofiber electrode materials:An asymmetric supercapacitor with high energy and power density[J].Adv Mater,2013,25(34):4746-4752.
• [58]HU Z,LI S,CHENG P,et al.N,P-co-doped carbon nanowires prepared from bacterial cellulose for supercapacitor[J].J Mater Sci,2016,51(5):2627-2633.
• [59]CHEN M,KANG H,GONG Y,et al.Bacterial cellulose supported gold nanoparticles with excellent catalytic properties[J].ACS Appl Mater Inter,2015,7(39):21717-21726.
• [60]LAI F,MIAO Y E,HUANG Y,et al.Nitrogen-doped carbon nanofiber/molybdenum disulfide nanocomposites derived from bacterial cellulose for high-efficiency electrocatalytic hydrogen evolution reaction[J].ACS Appl Mater Inter,2016,8(6):3558-3566.
• [61]HUANG Y,WANG T,JI M,et al.Simple preparation of carbonized bacterial cellulose-Pt composite as a high performance electrocatalyst for direct methanol fuel cells (DMFC)[J].Mater Lett,2014,128:93-96.
• [62]WU Z Y,LI C,LIANG H W,et al.Ultralight,flexible,and fire-resistant carbon nanofiber aerogels from bacterial cellulose[J].Angew Chem Int Edit,2013,125(10):2997-3001.
• [63]LIANG H W,GUAN Q F,ZHU Z,et al.Highly conductive and stretchable conductors fabricated from bacterial cellulose[J].NPG Asia Mater,2012,4:e19.
• [64]VOISIN H,BERGSTR?M L,LIU P,et al.Nanocellulose-based materials for water purication[J].Nanomaterials,2017,7(3):57.
• [65]MAHFOUDHI N,BOUFI S.Nanocellulose as a novel nanostructured adsorbent for environmental remediation:a review[J].Cellulose,2017,24(3):1171-1197.
• [66]LU M,GUAN X H,XU X H,et al.Characteristic and mechanism of Cr(Ⅵ) adsorption by ammonium sulfamate-bacterial cellulose in aqueous solutions[J].Chinese Chem Lett,2013,24(3):253-256.
• [67]JIN X,XIANG Z,LIU Q,et al.Polyethyleneimine-bacterial cellulose bioadsorbent for effective removal of copper and lead ions from aqueous solution[J].Bioresour Technol,2017,244(P1):844-849.
• [68]HUANG X,ZHAN X,WEN C,et al.Amino-functionalized magnetic bacterial cellulose/activated carbon composite for Pb2+ and methyl orange sorption from aqueous solution[J].J Mater Sci Technol,2018,34(5):855-863.
• [69]CHEN S,SHEN W,YU F,et al.Preparation of amidoximated bacterial cellulose and its adsorption mechanism for Cu2+ and Pb2+[J].J Appl Polym Sci,2010,117(1):8-15.
• [70]NATA I F,SURESHKUMAR M,LEE CK.One-pot preparation of amine-rich magnetite/bacterial cellulose nanocomposite and its application for arsenate removal[J].RSC Adv,2011,1(4):625-631.
• [71]OSHIMA T,KONDO K,OHTO K,et al.Preparation of phosphorylated bacterial cellulose as an adsorbent for metal ions[J].React Funct Polym,2008,68(1):376-383.
• [72]OSHIMA T,TAGUCHI S,FUJIWARA H,et al.Adsorption behaviors of bioactive amines and proteins on phosphorylated bacterial cellulose[J].J Ion Exc,2007,18(4):204-207.
• [73]CHENG R,KANG M,ZHUANG S,et al.Adsorption of Sr(Ⅱ) from water by mercerized bacterial cellulose membrane modified with EDTA[J].J Hazard Mater,2019,364(1):645-653.
• [74]SUN D,YANG J,LI J,et al.Novel Pd-Cu/bacterial cellulose nanofibers:Preparation and excellent performance in catalytic denitrification[J].Appl Surf Sci,2010,256(7):2241-2244.
• [75]洪秋林，郭必泛，朱佳妮，等.磺化酞菁钴-细菌纤维素复合材料的原位生物合成[J].杭州师范大学学报(自然科学版),2020,19(6):7-12.
• [76]ION V A,P?RVULESCU O C,DOBRE T.Volatile organic compounds adsorption onto neat and hybrid bacterial cellulose[J].Appl Surf Sci,2015,335:137-146.
• [77]SAKATA M,SAKAMOTO T,SHIMIZU M,et al.Aminated cellulose nanofibers for selective removal of endotoxins from protein solutions[J].Chem Lett,2017,46(2):194-196.
• [78]METREVELI G,W?GBERG L,EMMOTH E,et al.A size-exclusion nanocellulose filter paper for virus removal[J].Adv Healthc Mater,2014,3(10):1546-1550.