陈江旭;黄义梅;杨洪钦;郑莉琴;王瑜华;谢树森;

• 1:福建师范大学激光与光电子技术研究所医学光电科学与技术教育部重点实验室福建省光子技术重点实验室

摘要(Abstract)：

一氧化氮(NO)既能促进又能抑制癌细胞的增殖与转移,但是NO在癌细胞增殖与转移过程中所起作用的分子机理尚未明确.采用微孔板荧光检测技术观察NO对癌细胞钙离子浓度的调节作用,实验结果显示,外源性NO能使细胞内钙离子荧光强度显著增强,且增强程度与NO质量分数呈正相关;此外,NO引起的细胞内钙离子浓度增大主要是源于细胞内钙库的钙释放.研究结果有助于在细胞分子层面认识NO在癌细胞增殖与转移中的作用机制.

关键词(KeyWords)： 一氧化氮;钙离子;HeLa细胞;微孔板荧光分析仪;生物光子学

Abstract:

Keywords:

基金项目(Foundation): 国家自然科学基金资助项目(60978071);; 福建省自然科学基金资助项目(2010J01322)

作者(Authors): 陈江旭;黄义梅;杨洪钦;郑莉琴;王瑜华;谢树森;

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